کلاژن چیست؟

لایه بازال از یک ردیف سلول تقریبا چهار وجهی (شبه مکعبی) تشکیل شده که دارای میتوکندری فراوان و دستگاه گلژی تکامل یافته است.

 ترجمه به فارسی: بافتی بسیار سبک و ملایم داشته و فواید متعددی برای پوست دارد: بدون بستن منافذ پوست، عیوب چهره را پنهان می کند. روغن ماکادمیا، پوست را در تمام طول روز مرطوب نگاه می دارد. ویتامین B3 به پوست، درخشش طبیعی می بخشد. عصاره جو دوسر، پوست را تغذیه و ترمیم می کند. فاکتور ضدآفتاب 15 از پوست در برابر اثرات مضر خورشید محافظت می کند. پروتئین ابریشم، پوست را نرم و یکدست می نماید. کلاژن و روغن آرگان به کاهش خطوط ریز و چروک های پوستی کمک نموده و از پیر شدن پوست ممانعت به عمل می آورد.

 ترجمه به فارسی: بافتی بسیار سبک و ملایم داشته و مزایای متعددی برای پوست به ارمغان می آورد: بدون مسدود کردن منافذ پوستی موجب پنهان کردن عیوب چهره می شود. روغن ماکادمیا، پوست را در طول روز مرطوب نگاه می دارد. کمپلکس حاوی چند ماده معدنی مقاومت پوست را افزایش می دهد. ویتامین B3 و ویتامین C موجب اصلاح رنگ و افزایش درخشش پوست می شوند. عصاره جو دوسر به تغذیه و ترمیم پوست کمک می کند. فاکتور ضدآفتاب 25 از پوست در برابر اثرات مخرب آفتاب محافظت می کند. پروتئین ابریشم، پوست را نرم و یکدست می کند. کلاژن و روغن آرگان خطوط و چروک های پوست را کاهش داده و از پیری پوست ممانعت به عمل می آورند.

 ترجمه به فارسی: بالزام چیلی و فلفل حاوی ترکیبات ارزشمندی مثل فلفل قرمز، فلفل چیلی، زنجبیل، گزنه، منتول و اسانس های روغنی می باشد. فلفل قرمز و فلفل چیلی نرم کننده پوست بوده و شادابی پوست را افزایش می دهد. حرارت ناشی از تحریک پوست، موجب افزایش گردش خون مویرگی می شود. عصاره زنجبیل تولید کلاژن را افزایش داده و ساختار پوست را بهبود می بخشد. عصاره گزنه پوست را تسکین می دهد. این ژل ماساژ با برخورداری از منتول، احساس خنکی و طراوت را در هنگام ماساژ به پوست شما اعطا می کند.

 ترجمه به فارسی: بالزام چیلی و فلفل با برخورداری از ترکیبات ارزشمندی چون فلفل قرمز، فلفل چیلی، زنجبیل، گزنه، منتول و اسانس های روغنی بدن را تسکین بخشیده و موجب شادابی روح و روان بعد از یک روز کاری پرتنش می شود. فلفل قرمز و فلفل چیلی نرم کننده پوست بوده و موجب افزایش شادابی پوست می شود. حرارت ناشی از تحریک پوست، گردش خون مویرگی را افزایش می دهد. عصاره زنجبیل تولید کلاژن را افزایش داده و ساختار پوست را بهبود می بخشد. عصاره گزنه پوست را تسکین می دهد. این ژل ماساژ با برخورداری از منتول، احساس طراوت به پوست شما در هنگام ماساژ می دهد.

 ترجمه به فارسی: ماسک هیدروژل برچسبی دور چشم، غنی از کلاژن برای رطوبت رسانی پوست، افزایش حجم، خنک کنندگی و سفتی پوست اطراف چشم

ALARIA ESCULENTA — Edible seaweed high in essential fatty acids and antioxidants. A rich moisturizer, it stimulates the creation of hyaluronic acid within the skin and helps support collagen and elastin to promote skin elasticity. It has been clinically proven to significantly increase firmness when applied twice daily to the skin for 28 days. (INCI dictionary) 

AMINO ACIDS — Amino acids are “the building blocks” that make up proteins. Because proteins are necessary to every living cell and are involved in every major process in the body, amino acids are essential to health. Of the roughly 28 known amino acids, 80 percent are manufactured by the body. The others, known as essential amino acids, must be obtained from the diet. Amino acids support proteins in the skin (collagen, elastin, etc.) and, used in certain combinations, help regulate oil production in the skin and scalp. Human hair is made up of 18 amino acids, which is why many quality hair care products contain them. (INCI dictionary) 

ARGANIA SPINOSA — Argan Oil. Nutrient-rich oil, high in essential fatty acids and antioxidant vitamin E. Supports the skin’s collagen and improves softness and elasticity. In hair care products, it rehydrates and smoothes the hair cuticle to help reduce frizzing and add shine. (INCI dictionary)

ASCORBIC ACID — Vitamin C. Powerful antioxidant and nutrient, very beneficial to the skin. Plays an essential role in building collagen, the connective tissue that makes up 70 percent of our skin. Vitamin C is also a natural preservative, protecting both the oil and water phases of cosmetics. Ascorbic acid is a water-soluble form of vitamin C. (See also Calcium ascorbate.) (INCI dictionary) 

CALCIUM ASCORBATE — Ester-C® Topical. A patented form of natural vitamin C, both oil- and water-soluble, clinically shown to retain its potency longer than other forms.While ordinary vitamin C degrades quickly in skin care products, Ester-C® Topical is stable and delivers the full benefit of this powerful antioxidant, penetrating into deep layers of the skin to promote collagen production. (Ester-C® is a registered trademark of Inter-Cal Corporation.) (INCI dictionary)

CARNOSINE — Naturally occurring combination of the amino acids histidine and alanine, used in skin care products for its pro- tective and skin rejuvenating proper ties. An antioxidant and anti-in- flammatory, it protects collagen and elastin fibers in the skin from oxidative stress, improves elasticity and reduces wrinkles and other signs of aging. (INCI dictionary)

COLLAGEN — See Soluble Collagen. (INCI dictionary)

EQUISETUM HYEMALE, EQUISETUM ARVENSE — Horsetail, Bottlebrush. Nutrient-rich herbal high in silica, essential to collagen production. A vegan alternative to collagen treatments, it firms and refreshes the skin and promotes healing. Often used in conjunction with coltsfoot in hair care products, it strengthens the hair shaft and adds sheen and elasticity. (INCI dictionary)

HYDROLYZED ELASTIN — A naturally derived, water-soluble protein of bovine origin. Elastin is one of the three main proteins found in the skin, along with collagen and reticulin. Applied topically, it helps attract and retain moisture. (INCI dictionary)

SOLUBLE COLLAGEN — Dermal protein that makes up 70 percent of the body’s connective tissue. Applied topically, it helps attract and retain moisture to smooth and soften the skin, increase elasticity and diminish the appearance of fine lines and wrinkles. (INCI dictionary)

WHEY PROTEIN — A protein derived from milk. Helps suppor t the skin’s collagen. (INCI dictionary)

Collagen – Soluble collagen (INCI dictionary)

ARGININE: An amino acid that binds to the pure glycolic acid molecule. Once bonded, it allows for controlled delivery of glycolic acid into the skin over a prolonged period of time thus reducing irritation that usually accompanies AHA use. Promotes collagen synthesis and increases skin elasticity. (cellularskinrx.com)

CHLORELLA VULGARIS: Chlorella Vulgaris is a microalgae that stimulates collagen and elastin production while protecting these skin proteins from early cell death caused by inflammation enzymes elevated during stress. (cellularskinrx.com)

DARUTOSIDE: Also known as Siegesbeckia orientalis, Darutoside is a plant extract that is rich in emollients. By soothing the skin, decreasing inflammation, restoring collagen and promoting collagen production, this extract helps to improve skin elasticity and brightens surface appearance. Darutoside has been shown to stimulate tissue regeneration via collagen fibres which improves skin elasticity. (cellularskinrx.com)

FERULIC ACID: Ferulic acid is an excellent antioxidant, neutralizing free radicals,thus preventing premature aging of the skin caused by free radical damage to elastin and collagen. Ferulic acid acts synergistically with other antioxidants, specifically vitamin C and E, to double their ability to protect the skin from UV radiation. (Interestingly, Ferulic Acid's antioxidant activity is actually boosted by exposure to UV light.) The addition of Ferulic Acid to solutions that contain l-ascorbic acid helps to stabilize 90% of the vitamin C (l-ascorbic acid) and 100% stability is conferred upon Vitamin E (tocopherol). Used in F*a*C*E Synergy Serum. (cellularskinrx.com)

GREEN TEA EXTRACT: A powerful antioxidant that protects skin from free radical damage that causes premature aging. The polyphenols in green tea act as free radical scavengers soaking up these unstable molecules before they can damage the collagen layer. Green tea extract has also been shown to soothe, heal and calm irritated skin. (cellularskinrx.com)

L-ASCORBIC ACID: It is the most effective form of Vitamin C and acts as a powerful antioxidant. L-Ascorbic Acid is the only form of Vitamin C that is easily absorbed by the skin and is a key element in any anti-aging skincare regimen. Skin is exposed to a variety of environmental insults on a daily basis. UVA/UVB radiation, smoke, air pollution and stress all contribute to the free radical/oxidation process that breaks down the collagen layer of your skin. During this oxidation process, environmental insults cause the skin to form free radicals (O1 molecules) that need to attach to other molecules to become stable (O2 molecules). These free radicals attach to the skin's collagen molecules. This contributes to the breakdown of this collagen layer. Skin starts to look old and loses its natural firmness and elasticity. L-Ascorbic Acid protects your skin from environmental damage and prevents the formation of free radicals. L-Ascorbic Acid is necessary for collagen production and helps to stimulate your skin to produce healthy collagen layers. Over time, the L-Ascorbic Acid in the C + Firming Serum will help to reduce hyperpigmentation, lighten brown spots and improve the texture and firmness of your skin for a younger-looking, more radiant appearance. The 12% concentration of L-Ascorbic Acid in the C + Firming Serum is formulated at a lower ph to ease absorption. It is suspended in a simple stabilizing solution to maintain the effectiveness of the Vitamin C over time. (cellularskinrx.com)

MUNG BEAN SPROUT STEM CELLS: MMP enzymes have been identified as particularly damaging to the skin's extra-cellular matrix. Mung Bean Sprout Stem Cells protect collagen and the extra-cellular matrix from MMPs. The stem cells repair UV-damaged fibroblasts and reduce photo-induced inflammation that eventually leads to skin sensitivity and loss of elasticity. Used in Firming Densifier Active Treatment Moisturizer. (cellularskinrx.com)

OXIDO REDUCTASES: Oxido Reductases is a powerful antioxidant agent that helps to reduce the oxidation process that can lead to premature aging. Oxido Reductases acts as a free radical scavenger, neutralizing free radical molecules in the skin that can lead to collagen/elastin damage. Oxido Reductases has also been shown to have skin lightening properties. Used in Eye Bright Treatment Serum. (cellularskinrx.com)

PALMITOYL OLIGOPEPTIDE: Palmitoyl Oligopeptide (also known as palmitoyl pentapeptide, Dermaxyl, Matrixyl and Matrixyl 3000) is an engineered amino-peptide that when added to a culture of fibroblasts (key skin cells), stimulates collagen, elastin and glucosaminoglycans production. These are the key components of healthy-looking skin. Clinically proven to reduce wrinkle depth by increasing hyaluronic acid and collagen production, Palmitoyl Oligopeptide (PO)is a synthetic protein that is a fragment of collagen combined with palmitic acid to make it more lipophillic, to improve its stability and to enhance its affinity towards human skin. As with Palmitoyl Pentapeptide-3, one could look at PO as a man-made precursor to collagen. PO was developed through research to identify a substance that would behave similarly to retinoic acid but without its drawbacks, especially in regards to synthesizing collagen. The reported results are as follows: In vitro: Increases collagen production by the fibroblasts by as much as 350%. Increases hyaluronic acid production by the fibroblasts by as much as 146%. In vivo: The following statistics were gathered using image analysis of volunteers who used crèmes containing a 3% concentration of Biopeptide-CL for 28 days. Surface roughness -- Reduced 17% Mean depth of wrinkles -- Reduced 23% Depth of main wrinkle -- Reduced 39% Skin thickness -- Increased 4%. The increase in skin thickness was considered especially notable and contrasts with the 6% reduction of the skin thickness that occurs after 10 years of aging. PO is a potent active cosmetic ingredient without the adverse effects (including irritation, dehydration or long-term toxicity and instability) characteristic of retinoids. Used in CSRx Lip Remodeling Treatment, Intensive Eye Therapy Creme, Firming Peptide Eye Creme,  and Fresh Pout Lip Balm. (cellularskinrx.com)

PALMITOYL PENTAPEPTIDE 3: Clinically proven to regenerate the skin's upper layers by stimulating collagen production, thus thickening the epidermis. Palmitoyl Pentapeptide-3 is a synthetic protein that is a fragment of the C-terminal portion of collagen I (the most common type of the nineteen forms of collagen) combined with palmitic acid to make it more lipophillic, to improve its stability and to enhance its affinity towards human skin. One could look at Palmitoyl Pentapeptide-3 as a man-made precursor to collagen I. When this protein is added to cultured human fibroblasts it enhances the synthesis of collagen I, collagen III and fibronectin. In vitro, Palmitoyl Pentapeptide-3 was found to stimulate collagen IV synthesis by 100-327% and to stimulate hyaluronic acidsynthesis by 267%. In vivo Palmitoyl Pentapeptide-3 was found to stimulate collagen synthesis by 30-117%. Image analysis determined the effect Palmitoyl Pentapeptide-3 had on wrinkled skin. The six-month results are listed below, though significant results were seen in two months. Results: Mean wrinkle depth -- Reduced 17% Surface area: deep wrinkles -- Reduced 68% Surface area: moderate wrinkles -- Reduced 51% Mean density of wrinkled area -- Reduced 47% Skin roughness -- Reduced 16% Main wrinkle volume -- Reduced 24%. These results show that Palmitoyl Pentapeptide-3 had a dramatic effect on reducing the quantity and depth of wrinkles. It also improved surface smoothness. (cellularskinrx.com)

RETINOL: Retinol is pure active Vitamin A which is scientifically proven to produce healthy, plump skin cells. Because Retinol's molecular structure is small enough to penetrate the outer layers of the epidermis, it can repair deeper layers within the skin.  Collagen and elastin are positively impacted by the benefits of Retinol, as it stimulates the production of collagen in the skin layers, and helps to rebuild and repair elastin fibers. Retinol accelerates cell turnover, encouraging dead skin cells to naturally exfoliate more quickly, thus revealing healthy, fresh cells. It is an excellent ingredient that aids in the repair of sun damaged skin.  Retinol has been proven to be extremely helpful in the treatment of acne without the drying effects (cellularskinrx.com)

SOY PEPTIDES: Soy peptides stimulate fibroblast proliferation and increase collagen and elastin synthesis. This results in firmer-looking skin. Soy Peptides are used to help prevent proteinase activity (as a result of exposure to UV light and ozone) from degrading collagen bundles in the skin. They can also can help to lighten hyperpigmentation and act as an anti-irritant, reducing inflammation. Used in Eye Bright Treatment Serum. (cellularskinrx.com)

TETRAHEXYLDECYL ASCORBATE: Stable, oil-soluble vitamin C ester able to be used in cosmetic products with neutral to high pH. Protects from lipid peroxidation and limits melaninogenesis. Limits UV damage and stimulates collagen production. Used in Smooth Surface Instant Line-Filler. (cellularskinrx.com)

Elastin: Protein found in the neck ligaments and aortas of cows. Similar to collagen. Can’t affect the skin’s own elasticity. Alternatives: synthetics, protein from plant tissues. (peta.org)

Collagen: Fibrous protein in vertebrates. Usually derived from animal tissue. Can’t affect the skin’s own collagen. An allergen. Alternatives: soy protein, almond oil, amla oil (see alternatives to Keratin), etc. (peta.org)

1- مواجهه = Exposure مواجهه، در معرض قرار گرفتن، در تماس قرار گرفتن

overexposure = مواجهه بیش از حد
وسیله ای برنده که برای رفع موهای زائد بدن یا اصلاح صورت استفاده می شود
sun exposure = مواجهه با آفتاب

Exposure time = زمان تماس، زمان مواجهه

Store out of sun exposure = دور از معرض آفتاب نگهداری شود

exposure to toxic chemicals = مواجهه با مواد شیمیایی

apply 15 minute before sun exposure = پانزده دقیقه قبل از مواجهه با آفتاب استفاده شود

Mostly caused by sun exposure and hormonal imbalances = اغلب در اثر مواجهه با خورشید یا عدم تعادل هورمونی ایجاد می شود

Symptom of: eczema and rosacea,infections like scarlet fever andshingles, temperature exposure,stress = علائم بیماری هایی مثل: اگزما و روزاسه، عفونت هایی مانند مخملک و زونا، قرار گرفتن در معرض دما، استرس

2- نامنظم = Irregular نامنظم

irregular skin surface and texture = ناهموار شدن سطح پوست

3- لایسین = Lysine لایسین

LAUROYL LYSINE = ماده پودری که از اسید آمینه لیزین و اسید لوریک نارگیل به دست می آید. احساس ابریشمی را به پودرهای گریم اضافه می کند.

4- پرولین = Proline پرولین

5- نوسازی = Renewal نوسازی

skin renewal = نوسازی پوست

cell renewal = نوسازی سلولی

tissue renewal = نوسازی بافت

6- اپیدرم = The Epidermis اپیدرم

The dermal papillae (DP) are small, nipple-like extensions of the dermis into the epidermis. = درمال پاپیلا، برآمدگی های درم به داخل اپیدرم

stratum spinosum layer of the epidermis that is located between stratum granulosum and stratum germinativum = استراتوم اسپینوزوم لایه ای از اپیدرم است که بین لایه دانه دار و بازال قرار گرفته است

7- ضد پیری = Anti Aging ضد پیری، ضدپیری، ضد سالخوردگی

an anti aging facial = فیشال جوانسازی

anti aging ingredients = مواد ضدپیری

Anti-acne, anti bacterial, anti aging = ضدآکنه، ضدباکتری، ضدپیری

8- شناسایی = Identification

9- فرابنفش = Ultraviolet
Ultraviolet ray = اشعه فرابنفش 

UV, Ultraviolet = پرتوهای فرابنفش

ultraviolet or uv radiation = پرتوهای فرابنفش 

ultraviolet rays of the sun = پرتوهای فرابنفش خورشید

10- فرابنفش = Ultraviolet
Ultraviolet ray = اشعه فرابنفش 

UV, Ultraviolet = پرتوهای فرابنفش

ultraviolet or uv radiation = پرتوهای فرابنفش 

ultraviolet rays of the sun = پرتوهای فرابنفش خورشید

11- مهارکننده = Inhibitor
elastase inhibitor = مهارکننده الاستاز 

inhibitory potential = توان ممانعت

competitive inhibitor = مهارکننده رقابتی 

inhibitor of lipid accumulation = مهارکننده انباشت لیپید

MIC, Minimum Inhibitory Concentration = غلظت بازداری حداقل 

12- بدون چربی = Non-Greasy غیر چرب، بدون چربی

13- پیری پوست = Skin Explants اکسپلانت های پوستی

human skin explants = اکسپلانت های پوست انسان

14- کلاژن هفت = Collagen Vii کلاژن هفت

15- اسید آمینه = Amino Acid آمینو اسید، اسید آمینه
اسیدهای آمینه 

Peptide = short chains of amino acids = پپتیدها = رشته های کوتاه از اسیدهای آمینه

16- فیبروبلاست = Fibroblast فیبروبلاست
فیبروبلاست
the amount of UV radiation that will produce minimal erythema (sunburn or redness) within a few hours following exposure.
human fibroblastic collagenase = کلاژناز فیبروبلاست انسان

fibroblasts, a cell in connective tissue which produces collagen and other fibres = فیبروبلاست ها، سلول های بافت پیوندی که کلاژن و فیبرهای دیگر تولید می کنند 

17- فیزیولوژیک = Physiologic فیزیولوژیکی، عملکرد طبیعی

18- فیبروبلاست = Fibroblasts فیبروبلاست
the amount of UV radiation that will produce minimal erythema (sunburn or redness) within a few hours following exposure.
fibroblasts, a cell in connective tissue which produces collagen and other fibres = فیبروبلاست ها، سلول های بافت پیوندی که کلاژن و فیبرهای دیگر تولید می کنند 

19- فعالیت بیش از حد = Overactivity فعالیت بیش از حد

20- مواجهه بیش از حد = Overexposure مواجهه بیش از حد
وسیله ای برنده که برای رفع موهای زائد بدن یا اصلاح صورت استفاده می شود

21- ماتریس برون سلولی = Extracellular Matrix ماتریس برون سلولی 

ECM, extra-cellular matrix, extracellular matrix = ماتریس برون سلولی 

مطلب فوق را در شبکه های اجتماعی زیر با دوستانتان به اشتراک بگذارید