ماتریکسیل = matrixyl

matrixyl = ماتریکسیل، نام جاری یکی از پپتیدهای ماتریکین

MATRIXYL 3000: Also known as palmitoyl tetrapeptide-7. This next generation oligopeptide firms and decreases visible wrinkles within two months of daily use. Used in Firming Peptide Eye Creme and CSRx Lip Remodeling Treatment. (cellularskinrx.com)

MATRIXYL® SYNTHE®6: Facial architectural peptide supports 6 skin-rebuilding activities for a more organized cellular matrix. Signals skin to rebuild particularly where needed, especially the forehead and crow's feet. Natural volume is restored over time. Used in Firming Densifier Active Treatment Moisturizer. (cellularskinrx.com)

PALMITOYL OLIGOPEPTIDE: Palmitoyl Oligopeptide (also known as palmitoyl pentapeptide, Dermaxyl, Matrixyl and Matrixyl 3000) is an engineered amino-peptide that when added to a culture of fibroblasts (key skin cells), stimulates collagen, elastin and glucosaminoglycans production. These are the key components of healthy-looking skin. Clinically proven to reduce wrinkle depth by increasing hyaluronic acid and collagen production, Palmitoyl Oligopeptide (PO)is a synthetic protein that is a fragment of collagen combined with palmitic acid to make it more lipophillic, to improve its stability and to enhance its affinity towards human skin. As with Palmitoyl Pentapeptide-3, one could look at PO as a man-made precursor to collagen. PO was developed through research to identify a substance that would behave similarly to retinoic acid but without its drawbacks, especially in regards to synthesizing collagen. The reported results are as follows: In vitro: Increases collagen production by the fibroblasts by as much as 350%. Increases hyaluronic acid production by the fibroblasts by as much as 146%. In vivo: The following statistics were gathered using image analysis of volunteers who used crèmes containing a 3% concentration of Biopeptide-CL for 28 days. Surface roughness -- Reduced 17% Mean depth of wrinkles -- Reduced 23% Depth of main wrinkle -- Reduced 39% Skin thickness -- Increased 4%. The increase in skin thickness was considered especially notable and contrasts with the 6% reduction of the skin thickness that occurs after 10 years of aging. PO is a potent active cosmetic ingredient without the adverse effects (including irritation, dehydration or long-term toxicity and instability) characteristic of retinoids. Used in CSRx Lip Remodeling Treatment, Intensive Eye Therapy Creme, Firming Peptide Eye Creme,  and Fresh Pout Lip Balm. (cellularskinrx.com)

 مثال 2- یکی از معروف ترین پپتیدهای به کار رفته در محصولات آرایشی بهداشتی، بایوپپتیدی به نام ماتریکسیل یا همان پالمیتوئیل الیگوپپتید است. ماتریکسیل در غلظتهای بسیار پائین در فرمولاسیون کرم ها استفاه می شود.

 برای آگاهی بیشتر بروشور رک را دانلود و مطالعه کنید. پپتیدهای پیام رسان (مثل ماتریکسیل) چگونه عمل می کنند؟ کلاژن یک نوع پروتئین است. وقتی کلاژن شکسته می شود تبدیل به بخش های کوچکی با نام پپتید می شود. برخی از این پپتیدها دارای توالی خاصی از اسیدهای آمینه هستند که توسط فیبروبلاستها قابل شناسایی هستند. وجود این توالی خاص در پپتیدها به فیبروبلاست علامت می دهد که پوست کمبود کلاژن دارد. فیبروبلاستها با دیدن این علامت (این توالی خاص از اسیدهای آمینه) شروع به کلاژن سازی می کنند. ماتریکسیل به تقلید از همان پپتیدهای خاص که آن توالی خاص از اسیدهای آمینه را دارند ساخته شده اند. وقتی این بایوپپتیدها روی پوست مالیده می شوند در واقع به نوعی به پوست کلک می زنند و علامتی مشابه زمانی که کلاژن تخریب شده به فیبروبلاستها می دهند. به این ترتیب فیبروبلاست پوست شروع به کلاژن سازی می کنند.

MATRIXYL 3000: Also known as palmitoyl tetrapeptide-7. This next generation oligopeptide firms and decreases visible wrinkles within two months of daily use. Used in Firming Peptide Eye Creme and CSRx Lip Remodeling Treatment. (cellularskinrx.com)

MATRIXYL® SYNTHE®6: Facial architectural peptide supports 6 skin-rebuilding activities for a more organized cellular matrix. Signals skin to rebuild particularly where needed, especially the forehead and crow's feet. Natural volume is restored over time. Used in Firming Densifier Active Treatment Moisturizer. (cellularskinrx.com)

PALMITOYL OLIGOPEPTIDE: Palmitoyl Oligopeptide (also known as palmitoyl pentapeptide, Dermaxyl, Matrixyl and Matrixyl 3000) is an engineered amino-peptide that when added to a culture of fibroblasts (key skin cells), stimulates collagen, elastin and glucosaminoglycans production. These are the key components of healthy-looking skin. Clinically proven to reduce wrinkle depth by increasing hyaluronic acid and collagen production, Palmitoyl Oligopeptide (PO)is a synthetic protein that is a fragment of collagen combined with palmitic acid to make it more lipophillic, to improve its stability and to enhance its affinity towards human skin. As with Palmitoyl Pentapeptide-3, one could look at PO as a man-made precursor to collagen. PO was developed through research to identify a substance that would behave similarly to retinoic acid but without its drawbacks, especially in regards to synthesizing collagen. The reported results are as follows: In vitro: Increases collagen production by the fibroblasts by as much as 350%. Increases hyaluronic acid production by the fibroblasts by as much as 146%. In vivo: The following statistics were gathered using image analysis of volunteers who used crèmes containing a 3% concentration of Biopeptide-CL for 28 days. Surface roughness -- Reduced 17% Mean depth of wrinkles -- Reduced 23% Depth of main wrinkle -- Reduced 39% Skin thickness -- Increased 4%. The increase in skin thickness was considered especially notable and contrasts with the 6% reduction of the skin thickness that occurs after 10 years of aging. PO is a potent active cosmetic ingredient without the adverse effects (including irritation, dehydration or long-term toxicity and instability) characteristic of retinoids. Used in CSRx Lip Remodeling Treatment, Intensive Eye Therapy Creme, Firming Peptide Eye Creme,  and Fresh Pout Lip Balm. (cellularskinrx.com)